Lenvatinib mesylate
Lenvatinib mesylate
CAS: 857890-39-2
Molecular Formula: C22H23ClN4O7S
Lenvatinib mesylate - Names and Identifiers
| Name | Lenvatinib mesylate |
| Synonyms | E7080 Mesylate Lenvatinib mesylate lenvatinib Methanesulfonate 4-[3chloro-4-(N'-cyclopropylureido)phenoxy]-7-methoxyquinoline-6-carboxamide methanesulfonate 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide monomethanesulfonate |
| CAS | 857890-39-2 |
| EINECS | 812-398-0 |
Lenvatinib mesylate - Physico-chemical Properties
| Molecular Formula | C22H23ClN4O7S |
| Molar Mass | 522.95862 |
| Melting Point | >220°C (dec.) |
| Appearance | Form Solid, color White to Off-White |
| Storage Condition | -20°C Freezer |
| Physical and Chemical Properties | Bioactive Lenvatinib Mesylate (E7080) is a synthetic, orally active inhibitor of tyrosine kinase that inhibits vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet-derived growth factor receptor (PDGFRα), stem cell factor receptor (Kit (c-Kit)), and rearrangement during transfection (RET (c-RET)). Levatinib mesylate has potential anti-tumor activity. |
| Use | Application of lenvatinib is a multi-target tyrosine kinase inhibitor, which may play a role in a variety of cancers, so Eisai is still in the research of lenvatinib for other cancers, such as hepatocellular carcinoma, Non-small cell lung cancer, melanoma, breast cancer, lymphoma, ovarian cancer, etc., retrieved by the drug ferry data, there are 62 clinical research information related to lenvatinib. In July 2017, Eisai submitted a listing application for the first-line treatment of advanced hepatocellular carcinoma with lenvatinib to the US FDA and the European Drug Administration. In clinical trials, lenvatinib is superior to the current standard therapeutic drug sorafenib for advanced hepatocellular carcinoma. |
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Spot supply
Product Name: Lenvatinib Mesylate Visit Supplier Webpage Request for quotationCAS: 857890-39-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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